Breakthroughs Target the Killer Cancer Affecting McCain
A new drug that attacks the precise form of deadly brain cancer that has stricken GOP Sen. John McCain of Arizona is being hailed as a po...
CNS is developing Berubicin, a breakthrough drug for the treatment of the most deadly form of brain cancer.
Berubicin was created at MD Anderson Cancer Center, the largest cancer and research institute in the world.
Berubicin’s Phase I clinical trial yielded promising results showing clinical activity in 44% of patients*.
Berubicin is the first of its class of drugs to cross the blood brain barrier (BBB) and reach cancer cells in brain tumor patients.
Led by industry leading scientists and executives with decades of experience developing drugs and bringing medical products to market.
Signed a collaboration agreement with Reata Pharmaceuticals, a $700M+ NASDAQ listed company, to further advance the development of brain cancer technologies.
CNS intends to list on the NASDAQ in 2018.
*Study not designed to demonstrate safety and effectiveness
In the United States, an estimated 78,980 new cases of brain tumor are expected to be diagnosed in 2018. Of these, the deadliest form is Glioblastoma Multiforme (GBM), responsible for the highest number of cases of all malignant tumors, with 12,500 cases projected in 2017 and 12,760 in 2018.*
Glioblastoma is the type of brain cancer that killed Senator Ted Kennedy and Vice President Joe Biden’s son. Unfortunately, Senator John McCain was also recently diagnosed with this deadly disease.
GBM is the most aggressive and common primary brain cancer in adults. It is highly invasive, virtually incurable, and the primary target for our lead drug candidate Berubicin.
Despite decades of research, the survival outcomes for patients with GBM remain virtually unchanged, with a median survival time of 14.6 months. * CBTRUS report
Berubicin, was created at the MD Anderson Cancer Center by Dr. Waldemar Priebe. Dr. Priebe is the founder of CNS Pharmaceuticals.
Berubicin is considered a breakthrough technology because...
What is an anthracycline?
An anthracycline is a class of drugs that are among the most effective anticancer treatments ever developed and are effective against more types of cancer than any other class of chemotherapeutic agents for cancers like breast, ovarian, leukemia, lymphoma, testicular, and others.
While this class of drugs has been extremely successful at treating even the most aggressive types of cancers, unfortunately in over 60 years of clinical research, anthracyclines have NEVER been shown to cross the blood-brain barrier (BBB) and impact deadly brain cancers… until now.
The very promising results of the Phase I clinical trial of Berubicin in GBM patients, completed by Reata Pharmaceuticals, demonstrated significant anti-tumor activity in 44% of the treated patients.*
It consisted of 61 patients which were enrolled in two separate studies. Both dose finding and safety were studied in patients with GBM or other brain cancers.
Berubicin has also been granted Orphan Drug status by the FDA in the US.
In 2018, with the funding to be secured from this equity crowdfunding campaign and a planned NASDAQ IPO, CNS expects to commence its Phase 2(a) clinical trial of Berubicin for the treatment of GBM.
In late 2017, CNS entered into a collaboration agreement with Reata Pharmaceuticals, currently a $700M+ NASDAQ listed company, to further advance the development of brain cancer technologies.
*Based on all tumor cell lines so far tested, Berubicin has been significantly more potent than doxorubicin, more cytotoxic, and a more potent topoisomerase II poison.
*Study not designed to demonstrate safety and effectiveness
At 2 minutes and 44 seconds into the video above, there is an animation that will show you how Berubicin is able to cross the BBB and attack a tumor.
The current standard for treatment for GBM is surgery, radiation, and chemotherapy with Temozolomide (TMZ). TMZ, the current standard of treatment for GBM, has limited efficacy.
Drugs currently used for the treatment of other cancers are not effective for the treatment of brain tumors. The brain’s protective mechanism, the BBB, is responsible for shielding brain tumors from the existing and potential new anti-cancer agents. The BBB makes development of effective drugs for brain tumors very difficult.
The lack of progress in the treatment of GBM provides a tremendous opportunity to identify better drugs like Berubicin.
If approved, Berubicin has the potential to realize a multi-billion dollar opportunity as a stand-alone or combination therapy for GBM and other cancers.
Approximately 40% of GBM patients have a genetic variation, which makes their tumors initially more responsive to Temozolomide (TMZ). TMZ is the current standard of care for these patients. Nearly all of these patients will quickly become resistant to TMZ. Berubicin could be prescribed after TMZ’s failure.
In case of the remaining 60% of GBM patients, TMZ is ineffective and Berubicin could be prescribed as a primary drug treatment.
In 2009, Schering reported worldwide sales of temozolomide (TMZ) of $1 billion. Current numbers for temozolomide market share may be lower since launch of generics in 2013.
As of now, there is no standard of care for recurrent GBM. Bevacizumab (Avastin) is a recently approved by FDA drug for chemotherapy for glioblastoma at relapse; however it does not improve survival.
Short-term efficacy of the current standard of treatment and low survival rate of GBM patients and other related central nervous system malignancies, create a significant unmet need and financial opportunity.
Berubicin has the potential to become the standard of care treatment for recurrent and TMZ resistant GBM. CNS will plan future clinical trials to establish Berubicin as an upfront treatment for glioblastoma. If approved, CNS believes that Berubicin has the potential to realize a multi-billion dollar opportunity as a stand-alone or combination therapy for GBM and other cancers.
John M. Climaco, JD is the CEO of CNS Pharmaceuticals, Inc. For 15 years Mr. Climaco has served in leadership roles in a variety of healthcare companies. Recently Mr. Climaco served as the Executive Vice-President of Perma-Fix Medical S.A where he managed the development of a novel method to produce Technitium-99. Previously Mr. Climaco served as President and CEO of Axial Biotech, Inc., a DNA diagnostics company. In the process of taking Axial from inception to product development to commercialization, Mr. Climaco created strategic partnerships with Medtronic, Johnson & Johnson and Smith & Nephew. Mr. Climaco currently serves as a director of several public companies including Moleculin Biotech, Inc., pharmaceutical company focused on anti-cancer drug candidates. Mr. Climaco also served as a director of PDI, Inc., a provider of outsourced commercial services to pharma companies, and InfuSystem Holdings, Inc., the largest supplier of infusion services to oncologists in the US.
Sandra L. Silberman, M.D., Ph.D. is the Chief Medical Officer of CNS Pharmaceuticals. Dr. Silberman is a Hematologist/Oncologist who earned her B.A., Sc.M. and Ph.D. from the Johns Hopkins University School of Arts and Sciences, School of Public Health and School of Medicine, respectively, and her M.D. from Cornell University Medical College, and then completed both a clinical fellowship in Hematology/Oncology as well as a research fellowship in tumor immunology at the Brigham & Women's Hospital and the Dana Farber Cancer Institute in Boston, MA. Dr. Silberman has played key roles in the development of many drugs including Gleevec™, for which she led the global clinical development at Novartis. Dr. Silberman advanced several original, proprietary compounds into Phases I through III during her work with leading biopharmaceutical companies, including Bristol-Myers Squibb, AstraZeneca, Imclone and Roche.
Matt Lourie, CPA is the CFO of CNS Pharmaceuticals, Inc. Mr. Lourie has extensive management, accounting and financial experience. Mr. Lourie served as an audit partner of the PCAOB registered firm MaloneBailey where he oversaw audits and financial reporting of SEC registrants. In addition, he served as the Corporate Controller of a public company with over 300 locations across the country. Mr. Lourie is a graduate of the University of Houston where he earned both his Bachelor of Business Administration - Accounting and his Masters of Science in Accounting.
Donald Picker, PhD, joined the CNS team in November, 2017 with over 35 years of drug development experience. At Johnson Matthey, Dr. Picker was responsible for the development of Carboplatin, one of the world’s leading cancer drugs, acquired by Bristol-Myers Squibb and with annual sales of over $500 million. He also oversaw the development of Satraplatin and Picoplatin, third-generation platinum drugs currently in late-stage clinical development. Dr. Picker has significant experience in dermatological pharmaceutical discovery and development as well, having led projects for topical therapies in psoriasis, atopic dermatitis and acne.
J. George Gumulka, PhD, has more than 30 years of industrial and academic experience primarily in the R&D functions. George is an accomplished technology leader with strong international experience and with an excellent track record of successful new product and application. He has led innovation, technology and supported business efforts at several major global chemical companies including., Royal Dutch Shell/Shell Chemical Company, Kraton Polymers U.S. LLC, and Biospectrum Inc. His experience crosses multiple global industrial sectors including biotechnology, polymer and elastomer applications in consumer products, electronics, general industrial, commercial and residential construction, oil transportation, water purification to name a few.
Waldemar Priebe, PhD, Chairman of the Scientific Advisory Board, is a world renowned medicinal chemist and entrepreneur. Dr. Priebe is a Professor of Medicinal Chemistry in the Section of Immunobiology and Drug Carriers in the Department of Bioimmunotherapy at MD Anderson. Dr. Priebe is the inventor of more than 50 patents and the author of more than 200 scientific publications. As the founder or founding scientist of 6 pharmaceutical companies, including three listed on NASDAQ, Dr. Priebe has been integral in advancing several drugs through the pipeline, five of which entered clinical development. Dr. Priebe led the research that formed basis for the development of agents with high brain uptake (BBB crossing) and is the discoverer of our lead drug candidate Berubicin.
Sigmund Hsu, MD is fellowship trained and certified by the American Board of Psychiatry and Neurology, with extensive experience in the evaluation and treatment of neurological disorders in cancer patients. He specializes in primary brain tumors as well as brain and spinal cord metastases, cancer neurology and the treatment of chemotherapy neurotoxicity. Dr. Hsu has presented research at several national conferences, and his work has been published in numerous journals and textbooks. His most recent research has focused on novel therapies for recurrent primary CNS lymphoma, recurrent glioblastoma multiforme and intralumbar injections for cancer therapy, and he has several patents granted and pending for his treatments.
Our first step is to raise the maximum funding allowed on Republic, which is $1,070,000. This is the campaign that you are currently viewing now.
Shortly after, we plan to begin a Regulation A+ equity crowdfunding campaign on Sprout Equity and raise up to $15,000,000.
After we close out the Reg A+ fundraising round, we plan on listing on the NASDAQ stock exchange in 2018.
The smallest investment amount that CNS Pharma is accepting.
CNS Pharma needs to reach their minimum funding goal before
the deadline. If they don’t, all investments will be refunded.
The Crowd SAFE is an agreement for future equity in the startup,
meaning that it can convert to equity in the future.
The Crowd SAFE is an agreement for future equity in the startup, meaning that it can convert to equity in the future.
$100,000 – $1,070,000
CNS Pharma needs to raise
before the deadline. The maximum amount CNS Pharma is willing
to raise is $1.07M.
CNS Pharma was founded to bring breakthrough central nervous system drugs to market by utilizing new regulations recently approved by Congress. These new regulations allow individual investors, like yourself, the opportunity to be early stage investors as opposed to wall street bankers and venture capitalists.
Bringing a drug through a clinical trial and ultimately bringing it to market can take several years. Based on the compelling data relating to the mechanism of action of this novel drug, as well as initial clinical results in the Phase 1 study, this is planned as a multi-center Phase 2 study that will evaluate the efficacy of Berubicin in subjects who have Glioblastoma that has recurred or progressed following prior radiation therapy and temozolomide, which are the standards of care for newly diagnosed Glioblastoma. Approximately sixty (60) patients will be entered. Efficacy will be measured in terms of progression-free survival (PFS), which is a major endpoint in studies of Glioblastoma, using accepted methodology, corticosteroid usage, and neurologic status. All of these are considered important in terms of a disease that after failure of primary therapy is almost uniformly fatal. Median PFS is the primary efficacy endpoint defined as the number of months from the date of the first dose of berubicin to the date of first documentation of an event (progressive disease per standard radiographic criteria or death due to any cause). Note that in Glioblastoma, PFS and overall survival (OS) are strongly correlated, indicating that PFS may be an appropriate surrogate for OS. Compared with OS, PFS offers earlier assessment and higher statistical power at the time of analysis. We intend to keep our shareholders updated with press releases as we progress through the process.
No, we plan to license or develop additional Central Nervous System (CNS) anti-cancer drugs in the future to have a more diversified portfolio of drug candidates.
Subsequent to this fundraising campaign, we plan to raise funds under a Tier 2, Regulation A campaign. Our goal is to raise up to $15,000,000 in that campaign to fund our Phase II trials of Berubicin.
We plan to begin a Regulation A+ equity crowdfunding campaign on Sprout Equity and raise up to $15,000,000. After we close out the Reg A+ fundraising round, we plan on listing on the NASDAQ stock exchange in 2018, at which time investors could choose to sell their equity position or not.
Berubicin has no competitors that have proven to cure Glioblastoma. That said, the current standard of care involves surgical resection followed by radiation and treatment with Temozolamide. Almost all patients unfortunately still die of the disease following this program. There are also at least 23 ongoing Phase II or Phase III clinical trials of different combinations of drugs, any one of which might be effective against Glioblastoma. Of the many previous clinical trials, none have successfully provided a cure for Glioblastoma.
This capital will be used to fund early work needed to prepare for Berubicin’s Phase II Clinical Trial. This may include beginning production on the basic materials used to create Berubicin, paying the salaries of employees and general & administrative expenses. We have a tremendous advantage in that our collaboration agreement with Reata Pharmaceuticals enables us to use all the data from their 2009 Phase I study of Berubicin. As we mentioned earlier, we also intend to complete an IPO with an offering of up to $15,000,000 later this year. Those funds will be used in part to conduct this development work.
We believe Berubicin has the potential to become the standard of care treatment for recurrent and Temozolomide (TMZ) resistant Glioblastoma. CNS will plan future clinical trials to establish Berubicin as an upfront treatment for Glioblastoma. Based on currently available sales figures for TMZ, if approved, the initial market size for Berubicin could be up to $1 billion.
CNS Pharma successfully raised $628,558 from 666 investors on June 12, 2018
Pretty cool idea! Very excited to be part of it!!!!!!Oliver JamesInvested about 1 year ago
I believe in the techShea RalphInvested about 1 year ago
We love this idea and are so glad that normal families like ours are able to participate in these early stages. This is usually only for the very rich! Thank you for the opportunity.Maria JamesInvested about 1 year ago
I invested because it sounds that BERUBICIN is a drug that it's needed.FABIOLA JAMESInvested about 1 year ago
I believe in the mission.Michael GradInvested about 1 year ago
I invested because of the productTOMMY JAMESInvested about 1 year ago
I love biotech!Jason SundarInvested about 1 year ago
I want to help gleoblasta Patient’s and make moneyAndrew HaagInvested about 1 year ago
Breakthrough therapy. Excited about its potential.John GloverInvested about 1 year ago
It seems like a great opportunity and cheap valuationBill GlaserInvested about 1 year ago
I am excited about the possibilities of this drug.Robert WonishInvested about 1 year ago
I invested because I believe in MD Anderson and the people that are associated with this great institution. And I believe that ANY drug that can give a family additional time with their afflicted loved one is worth a shot!Allen TommyInvested about 1 year ago
I invested because I believe in MD Anderson and the people that are associated with this great institution. And I believe that ANY drug that can give a family additional time with their afflicted loved one is worth a shot!Tommy AllenInvested about 1 year ago
MD Anderson is a leader in cancer research and this is a highly experienced team. Having even limited early data showing activity in GBM is monumental. If this can be repeated in future trials, it will be a huge win for patients...and shareholders!Walter KlempInvested about 1 year ago
I believe in the technology. I have been tracking this compound for many years and I am glad it is going back into clinical trials.David RobinsInvested about 1 year ago
I loved finding out about this technology! Especially since it comes from MD Anderson Cancer Center!Daniel AmeduriInvested about 1 year ago
i believe in this management team and its ability to address brain cancer.Mike PruittInvested about 1 year ago
Because it's a great causeAhmed AlomariInvested about 1 year ago
I'm so excited to lead CNS Pharma. It's an honor to work with such a world-renowned and passionate team, all of whom are laser-focused on one thing: Developing game-changing therapeutics for central nervous system cancers.John ClimacoInvested about 1 year ago
As a former researcher at the Allen Institute for Brain Science, I'm well aware that Glioblastoma is always fatal. With CNS holding a promising molecule (developed at MD Anderson) that crosses the blood brain barrier, the investing decision was easy.lili estinInvested about 1 year ago
As a Physician, I see the potential that this drug has to save lives. CNS Pharm has the technology to develope many drugs, and the potential is there to cure several diseases of the nervous system and the brain.Joel CherdackInvested about 1 year ago
I believe in cancer research.Jonathan CamarilloInvested about 1 year ago
The technology is amazing and the need is so great!Michael DuBowInvested about 1 year ago
It has a strong prospect for rapid growth based on prospectus.Matt HolmInvested about 1 year ago
I'm very excited to be a part of this breakthroigh technology and to see how it could potentially save lives in the future!Tommy UhrInvested about 1 year ago
I invested this because I truly believed this would help many many patients that in needs of help and hopefully I will be witnessing the success of this new invention! And I am so looking forward to it and wish nothing but the best!!!Hang kuen LeungInvested about 1 year ago
great opportunity to invest in the latest medical technology and support a worthy causeMingzhao XuInvested about 1 year ago
Possibility to contribute to such an effort to aid an illness is great.Scott MarshallInvested about 1 year ago
I believe is an excellent initiative and also that it will be a very successful oneMarco MatoukInvested about 1 year ago
I have been convinced that drugs like Berubicin will effectively supplant surgery and radiation for certain malignancies.John HardyInvested about 1 year ago
There is a clear need for better treatment options in glioma's. Hopefully CNS Pharma can improve the prognosis of these patients.Mark WeninkInvested about 1 year ago
My Mom's partner has this cancer and is a 40 month survivor perhaps due to a similar clinical trial.David BillingsleyInvested about 1 year ago
I invested $250.00 because of my son, who at seven years old, passed away 20 years ago from Brain Cancer (Brain Stem Glioma).Catherine CarridoInvested about 1 year ago
Brain cancer and cancer in general is a terrible thing to be diagnosed with. Patients need all the help they can get.Lance KeastInvested about 1 year ago
Close friend just died from brain cancer.Walter J. BayerInvested about 1 year ago
Sounds like a good opprotunityJohn StricklandInvested about 1 year ago
I invested because we need this oneYanique EdouardInvested about 1 year ago
I think this could be huge.Thomas CalhounInvested about 1 year ago
This drug could be lifesaving, and the science makes sense. Any improvement above TMZ will be excellent progress.John WalshInvested about 1 year ago
like productjim mooneyInvested about 1 year ago
I invested because my wife died from a glioblastoma 15 years ago, even after 2 successful surgeries, radiation, and chemo. I want to help find a successful treatment so others can have a better chance of surviving this very difficult form of cancer.John LaMacchiaInvested about 1 year ago
Glioblastoma is a terrible condition. It needs to have successful treatment. Here's hoping you can make a difference.Art GrossInvested about 1 year ago
I like my money crow $250.00Santo SiragusaInvested about 1 year ago
i bielive in a progress i new discovery of medecinemilosav zivkovicInvested about 1 year ago
I invested $250.00 in hopes of accelerating research in one of the most devastating and elusive types of cancer that has, in the past, evaded treatment.Robert SchmidtInvested about 1 year ago
I like what they're doing to cure cancerArnold ShapiroInvested about 1 year ago
Family history of brain cancer.Andrew BoydInvested about 1 year ago
I invested because I believe in medical advancements.Brenda Ford JonesInvested about 1 year ago
I believe that the medicine that i am investing in with help a lot of people with stage 4 brain cancer.geraldine gatewoodInvested about 1 year ago
contributing my quota to a healthy and happy worldTeslim AkinsadeInvested about 1 year ago
I feel this company has a great potential to bring this new drug to market and that there will be a successful future for CNS Pharma.Dale BessellInvested about 1 year ago
It seems it could be successful.Taoli LiuInvested about 1 year ago
Seeking to invest in innovation & technology.Leland FongInvested about 1 year ago
I've had a very close friend die of an inoperable brain tumor several years ago. I see a great need for this type of drug that breaks the brain/blood barrier in order to reach and destroy this type of tumor!James ForakisInvested about 1 year ago
iy.lyc.tes.aproch.the.heltisrael herskovicInvested about 1 year ago
To grow wealthGeoffrey HainesInvested about 1 year ago
Investing from the heart hopefully will benefit the thousands that will live because of the research performed by CNS Pharma.phillip irvingInvested about 1 year ago
It sounds like a great plan for success.Antionette MooreInvested about 1 year ago
I thought that it would be a good investment, $250Merlyn HyersInvested about 1 year ago
There should always be new treatment options and methodologies for fighting cancer.Matthew BurrowInvested about 1 year ago
I invested because of the possibility CNS can help cancer patients.James TracyInvested about 1 year ago
I invested in CNS Pharma, because I firmly believe in the company's mission statement to further advance its vision in eliminating glioblastoma multiforme (GBM) and other brain related cancers of the human mind.Khuzema SavaiInvested about 1 year ago
I think its a great porject which i want to be part of it.Abdulla AlneyadiInvested about 1 year ago
this could potential save livesjohannes w ruitermanInvested about 1 year ago
I have experience with other pharma companies that have needed investment money at this stage. The product looks like a winner.Scott AndersonInvested about 1 year ago
I have had this particular brain tumor, and though in remission, it may still come back. This cure is important to me.Raymond EllisInvested about 1 year ago
I invested I believe this product will save a lifeGholi GholipourInvested about 1 year ago
You will see this through, you will go public, then bought up by big pharma, then I sit in my chair and count my 💰💰aHarry PloumenInvested about 1 year ago
Sounds interesting an potentially life changingLeo LibermanInvested about 1 year ago
Want to see those with this cancer have a chance to survive. I knew a 50 year old man with several children--some young--who battled this cancer for two years. His death just devastated his wife and kids.Terrence KissellInvested about 1 year ago
I invested because we need to get rid of cancer!scot mcdonaldInvested about 1 year ago
I invested in CNS Pharma because ... I recently lost my mother (about 2yrs ago) to BREAST CANCER. And even though this was different type of cancer disease, I'm very hopeful that CNS Pharma will medically find a cure for all future CANCER DISEASES.Kelvin CoxInvested about 1 year ago
i love it.Pete FoulkInvested about 1 year ago
Have a friend with this terrible cancerJoel McleodInvested about 1 year ago
My first wife died of brest cancer. She was treated at MD Andrerson.Dennis MurphyInvested about 1 year ago
Your going to make me moneyLoren DyllaInvested about 1 year ago
Sounds like CNS has a genuine goal to achieve success.Oscar ElbaumInvested about 1 year ago
My career was in a health-related field.David KranzInvested about 1 year ago
i am too well aware of the medical challenges in treating brain tumorswilliam wrightInvested about 1 year ago
first time try outjohnlong xiongInvested about 1 year ago
I have a friend with this terrible condition. My hope and prayer is that your product helps saves the lives of many people!Tim BalinInvested about 1 year ago
I saw close friends suffering from brain cancerclinton cheongInvested about 1 year ago
Like to support this cancer research helping others with your goal in helping others , with cancer treatment.Paul DriskellInvested about 1 year ago
Lost my wife to GBM. Nothing out there works.David ScarboroughInvested about 1 year ago
I invested to see if the medical field have created a breakthrough in medicine by shrinking/ destroying brain tumors. This is something I want to be apart of!Sandy DavisInvested about 1 year ago
Cancer cures and treatment advances are needed nowCindy SobieskiInvested about 1 year ago
There is a very strong need for a therapy that will help cure Glioblastoma and it appears that CNS is on the right track for doing this. Also, being associated with MD Anderson further supports the work CNS is doing.Joel ShaneInvested about 1 year ago
i believe in the work at Andersonharry pettitInvested about 1 year ago
Hoping they succeed in helping GBM patients.Dawn HuffmanInvested about 1 year ago
In honor of my sister-in-law.Philip OvittInvested about 1 year ago
This company has great potential.Kinson AuInvested about 1 year ago
GBM therapies are a real unmet medical need with little advance in overall or symptom free survival in the last decade - despite huge advances in most other cancers due to PD-1 inhibitors and similar approaches. A drug that penetrates BB may help.Evan SteinInvested about 1 year ago
I have glioblastomaKaren ChakiryanInvested about 1 year ago
I am retired and my wife and I have very little income saved for our retirement so I am hoping that this investment will come true to what I have been reading about it that's why I'm investing 500.00 so they can make it into huge success. thanksMichael BockInvested 12 months ago
My aunt has glioblastoma and I believe in the potential of improved treatment options.Peter LoparcoInvested 12 months ago
Good workAhmad KhalifaInvested 12 months ago
Hopefully CNS Pharma will shed new light on the horrific disease of brain cancer.Ina FineInvested 12 months ago
my wife died of this type of brain cancerSteven PetersonInvested 12 months ago
More and more people receive the unfortunate diagnosis of cancer. This new concept and drug is revolutionary. I want to be at the forefront of this new medical technology that has the potential to safe countless lives in the future.Yves BolducInvested 12 months ago
sound like a good investmentChantal VoltaireInvested 12 months ago
social impact!! hoping for very successful resultsElias TypaldosInvested 12 months ago
I believe its science is breakthrough and will benefit patients!Baiping GuoInvested 12 months ago
I am a nurse and I work with dementia patients. I will be an honorFATMATA BARRIE-TEAMERInvested 12 months ago
I have personal experience with GBM and other forms of Brain Cancer. Having lost many friends to this horrible disease I know how important it is to have drugs that can pass through the blood brain barrier.Ken ThuroInvested 12 months ago
Diversifying my investments.Luis VillarrealInvested 12 months ago
CNS has developed a promising treatment for many patients.Cody HeisingerInvested 12 months ago
believe in the visionWinson Wing Sun LiuInvested 12 months ago
I am a Glioblastoma csncer patient.Barry GrimesInvested 12 months ago
It is very interested for the first timeGi Jun NamInvested 12 months ago
Unique positioning in healthcare.Rama Prasad PandaInvested 12 months ago
1. To help find cures and help save lives 2. Diversify my investmentsNasser MarafihInvested 12 months ago
This is a major technological breakthrough that has a real chance to impact a lot of lives in a big way.Joshua JonesInvested 11 months ago
Any cure for cancer is always possible and here’s hoping this will help! YesSharon ShemtovInvested 11 months ago
Have lost many family and friends to cancer. It's time we put a stop to all these tragic deaths.Ty HudsonInvested 11 months ago
curing cancer, enough said $1000Carmine BaroneInvested 11 months ago
I love the potential.Kalman KaplanInvested 11 months ago
2018 IPO and good drugPatricia LalandeInvested 11 months ago
I want to be a part of the solution.Junaid MianInvested 11 months ago
A possible cure for this horrible brain cancer is fantastic. Even if my investment succeeds or not-for-profit it will have been worth the chance to see your team's efforts in succeeding. God speed!Loren RosethInvested 11 months ago
I love the opportunity to help cure cancer.Brian ChrestInvested 11 months ago
I love that they let me. I love what they are doing. I love that they want others to benefit.Kathy EllisInvested 11 months ago
Cancer has been one of the hardest diseases to eradicate. My father was a leading Oncologist, now retired, fought hard against it all his life.Ken HakomoriInvested 11 months ago
investing in myself to earn my financial freedom and making the world a better place in the processjose valdezInvested 11 months ago
I invested in CNS b/c of potential to cure, not treat, this disease.Robert RudzonisInvested 11 months ago
Having worked as a registered nurse for over twenty years I have personally seen the horrible effects a disease like cancer can have on an individual and their family.Matthew GoffInvested 11 months ago
I would love to see people with Brain Cancer have better chance of survival and to live a long and healthy life. Im Praying that CNS Pharma has the solution!!Tom JanottiInvested 11 months ago
I lost my wife to cancer. I couldn't save her, at least if I could help find a cure to save another life, we will be happy.Prasanna AirodyInvested 11 months ago
Highly innovative and brilliant biotech venture .Kapil KapoorInvested 11 months ago
This looks like a very good opportunity!David BerndtInvested 11 months ago
Invested $500 05/18/2018 in hopes that not only will this anthracycline work for glioblastoma but other cancers as well.Tom RichardsonInvested 11 months ago
I have too many family members and friends with cancer. We need to do all that we can.Russ PetersonInvested 11 months ago
Trust Account InvestmentWalter LewisInvested 11 months ago
Berubicin is very promising drug for treating Glioblastoma and I would like to be a part of bringing it to market.Louis ReveronInvested 11 months ago
to be part of something bigWilliam CrosbyInvested 11 months ago
I'd like to help people with cancer!Rick deGeurinInvested 11 months ago
Any potential way to help save lives is important.Michael LeeInvested 11 months ago
Beating the insidious disease is at the forefront of my existence!Aaron HartleyInvested 11 months ago
It is a privilege for me to invest in this Company which help improve the health of people in the United States.Fernando PereiraInvested 11 months ago
we must win the fight against brain cancer!!!!Nelson perezInvested 11 months ago
the proposed treatment sounds exciting for treatment for such a horrible diseaseDavid HendricksonInvested 11 months ago
high potential impact of treatmentMichael TeskeInvested 11 months ago
The philosophy of the company and the potential for making a great contribution to medicine and humanity is rewarding.Reza AliakbarInvested 11 months ago
To finally see a. Trial that works.Chris JohnsonInvested 11 months ago
i beleave some day there will be a cure for all cancers i invesded 500.00RICHARD LUMNAHInvested 11 months ago
I believe in this great idea.Tobias HoeltgeInvested 11 months ago
Solid and experienced management structure in breakthrough technology. Should be a winner for the world!Patrick HealyInvested 11 months ago
I BELIEVE IN THE GOALS OF CNSDONALD MORTONInvested 11 months ago
My wife is a nurse, she worked in Neural recovery . She told me about the death sentence of this Cancer, $500.00 is towards the cure.Pat FullerInvested 11 months ago
I invested because I'd like to see this terrible form of cancer eradicated as soon as possible.Seth PeylaInvested 11 months ago
I know some people who have suffered and died from this terrible disease.Ronnie KingInvested 11 months ago
I invested because I believe that you can help save a lot of lives with the new drug that you are developing for brain cancer.Lowell EnlowInvested 11 months ago
I believe this company is on the threshold of an incredible cancer fighting system that will save countless lives in the near future.ron HootmanInvested 11 months ago
I am a member of crowdability, and have invested in a medical pot startup. I want to make some money, to help family and leave something for my son. Your breakthrough looked very promising, hence my $2200.00 investment. I was limited by incomeDaniel PerryInvested 11 months ago
I invested because my father died of stage 4 glioblastoma.Ernest PasionInvested 11 months ago
I invested because I want to help fight against Cancer!!Ana RamirezInvested 11 months ago
i invested because my father was taken by cancerDarran WebbInvested 11 months ago
Your team seems to be committed and looking to the future to cure several different cancers.Fayette PerryInvested 11 months ago
I invested because this is the only formula that crosses the Brain Blood Barrier, THE ONLY ONE, and it works as advertised. This will have a huge impact on hundreds of thousands of lives. Just don't let 'Big Pharma' buy it and bury it to no benifit.Nels ReedInvested 11 months ago
I invested because I believe that berubicin with CNS Pharmaceuticals will really work and be a blessing for millions of people worldwide battling cancer.Laura BacinichInvested 11 months ago
Because l think it is a great opportunity to help cancer patients get the help that is needed, now the 300.00 dollars was just a shot at investing, but we will see, it's about helping cancer patients, not how much money that can be made.Billy TidwellInvested 11 months ago
Technology designed to treat the brain cancer can possibly revolutionize the treatment process.Sumit HandaInvested 11 months ago
CNS Pharma is into important missionBen KalskyInvested 11 months ago
It sounds like an amazing discovery which will be life saving.robert kaczenskiInvested 11 months ago
Because it looks like a promising product-treatment. If they can live up to their promises it should be profitable!Eva BeckerInvested 11 months ago
a member of my family died of cancer leaving a hole in our lives. if this could make a difference then I am fully invested.daniel rohrsInvested 11 months ago
I am hopeful for this treatment.Ann SchulerInvested 11 months ago
As a nurse, I would be happy to think I have helped fund a project like this that might stamp out another kind of cancer!Anne BrownInvested 11 months ago
I love the potential for what this can achieve.James KaastrupInvested 11 months ago
cancer needs to be stoppedMarie T ThompsonInvested 11 months ago
iI have lost alot of close family member's and think this company has a great futureWilliam SkylesInvested 11 months ago
I just want to do my part and help out in any way I can to see a possible cure for cancer be brought to the masses. This is potentially groundbreaking and an opportunity to invest in it is something I could not pass up. Best wishes to the team.Ronald (RJ) MarkoeInvested 11 months ago
This drug could be a major player in defeating cancer. Our family supports Dr. Monje at Stanford and Jim Olson at the Fred Hitch lab and we’ve seen our funds produce results in this very important fight, having lost far too many loved ones to cancer.Lindsay MilleaInvested 11 months ago
A common thread through humanity is our vulnerability to life-changing diseases. I'm excited to invest in a company that will help so many people live longer lives.Christian MartineInvested 11 months ago
The promising applications and potential of the productIan SinnisInvested 11 months ago
The goal is noteworthy and could benefit many people. Best wishes for CNS Pharma's success.Edward KonczalInvested 11 months ago
I invested in CNS because i believe is it for a good cause, helping science to develop ,and to help us back in the future ,and also i think is it a good investing opportunity, that it is been giving to us.thank you very much!Albert FraceaInvested 11 months ago
I invested because I believe this is very important work and I hope that this company can help to save many lives.michael baylorInvested 11 months ago
This is a major step forward in the fight against brain cancer for which there are very limited options available. These promising early results provide hope for those affected and will help drive further R&D in an under served area of oncology.Anikait SharmaInvested 11 months ago
Important work!Vera StarczakInvested 11 months ago
Aside from its potential financial returns, this investment has its worthy cause in savings lives. Who knows where this will extend its power to heal beyond cancer of the brain.Augusto GavinoInvested 11 months ago
I wanted to invest because my mother died from brain cancer.Jason SchaefferInvested 11 months ago
I invest in the future, medical and technology is the future.Joseph LombardoInvested 11 months ago
I believe in complete body health. Either through natural methods or scientific.Javona HinesInvested 11 months ago
Hopefully branches to other treatments and cures. In memory of my mother.Rafael MateoInvested 11 months ago
I believe in what they are hoping to achieve.Todd RengerInvested 11 months ago
It's a valuable cause. I want them to succeed.Michael MetzInvested 11 months ago
Multiple founders and CNS is the next thing.Patrick DangInvested 11 months ago
I believe in any good cause that can possibly cure Cancer. My father passed away from Acute Leukemia and my sister is a Stage 3 Colon Cancer survivor. My sister's ex husband was just diagnosed with a brain tumor.Gregg CarlsonInvested 11 months ago
I Invested to help bring these findings to the public.Lee Roy GeorgeInvested 11 months ago
strictly from my perspective, having observed pharma and biotech companies in the past, these types of investments can be highly lucrative despite inherent risks.Alex GlicksteinInvested 11 months ago
as an investment - $500Kiran ShahInvested 11 months ago
as an investment - $250Sareeta ShahInvested 11 months ago
as an investment - $250Kinar ShahInvested 11 months ago
I want to be an investor and this company has a product that will hopefully help those suffering.Laura WinkelInvested 11 months ago
Small investment in CNS can be a big contribution in the lives of patients with brain cancer.Vipul PatelInvested 11 months ago
Proud to support great companies!Travis HuffInvested 11 months ago
We need to find an answer for Cancer!! The company sounds like it is on the right track and I want to be a part of it.Michael HunsuckerInvested 11 months ago
This company's innovation and approach to cancer research is inspiring.Charlene RobertsInvested 11 months ago
I am investing in this product because it will make a difference in the life of a lot of people, and if in any small way I can be part of this breakthrough I want to make a small contribution to continued its' researched.Cosmas SmithInvested 11 months ago
One day this technology would help others prepare to administer assistance to those in need.John MorroInvested 11 months ago
a worthy causeHenry GilkesInvested 11 months ago
I believe in the objective of the promotorsUtpal DoshiInvested 11 months ago
Had and have to many friends whose lives were ruined by this terrible disease.Jerry CullitonInvested 11 months ago
Wife died of brain cancer and hope this is something that will save others. $500.00 investmentDerek HoldenInvested 11 months ago
We lost our son at age 46 to Glioblastoma and wanted to do what we could to help find a cure for this terrible diseaseMartin P InglinInvested 11 months ago
I support the search for cures for cancer.Alyssa KennedyInvested 11 months ago
My father was in excellent health at 83 when diagnosed with glioblastoma but died within 5 months. I wish something like this had been available! Because of money I inherited from him and invested, there may be a better chance for someone else.Patricia BeardInvested 11 months ago
I am an MD. I have had 2 good friends die of this disease.Shawn MoreheadInvested 11 months ago
It's a great cause.Nelson AcessInvested 11 months ago
It is good ideal to discovery to cure patient. It is not only safe patient 's life and it will be safe family's patient 's heart.Natthan TakprachyakulInvested 11 months ago
I invested because I hate cancer and I hate diseases. Hoping this company continues to scale research wise and financially.Chris ChristmanInvested 11 months ago
Drugs ability to cross the BBB and promising clinical trials.Tom StramerInvested 11 months ago
Promise of a drug that crosses BBB in GBMs; an unfilled area of GBM treatmentNitin ChandramouliInvested 11 months ago
Drug highly likely to gain FDA approvalJohn BangstonInvested 11 months ago
My father was diagnosed with a glioblastoma and fighting! We need to find a cure and fast to beat this deadly disease. I believe this is the right steps in finding a cure!Francesco BiancamanoInvested 11 months ago
I invested because of the potential of a quick exit. This is a breakthrough that will likely be scooped up by a big player or a great IPO.Lucas NorrieInvested 10 months ago
I invested because my father died of brain cancer in 1967. My prayer ever since then has been for someone to find a cure.Thomas BickerstaffInvested 10 months ago
I invested because we’re talking about a drug to help eliminate brain cancers; enough said. Gamechanger for the medical community.Gregory AndersonInvested 10 months ago
I support advanced/advancing technology to solve medicine's most difficult problems and I believe that CNS Pharma's technology/solution holds great promise in treating CNS cancers.Robert LindemuthInvested 10 months ago
I want to see a very real solution to this insidious type of cancer.Ken IgnacioInvested 10 months ago
I read their Form C, read up on backgrounds of founders, AND because CNS was rec by an advisory service to which I subscribe.mary robin jurkiewiczInvested 10 months ago
CNS Pharma is working on a portion of healthcare that could potentially change the industry, and help millions of lives. By being on Republic, they are crowdfunding a traditional industry- the perfect mix of social impact and disruption!Avery KondaInvested 10 months ago
This drug will change the game in GlioblastomaTed SindlingerInvested 10 months ago
I want to find a cure for glioblastoma and it is my first investment to earn needed income.Sharon McGillInvested 10 months ago
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